Valget af kraftigt virkende medicin i smertebehandling er en opvejning mellem bivirkninger og virkning samt hvor stærke smerterne er.defineres som smerter, der er forårsaget af en skade eller sygdom, som afficerer det somatosensoriske nervesystem. Neuropatiske smerter kan skyldes beskadigelse af nervebanerne på ethvert sted fra terminalerne på
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